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HER2-Low Breast Cancer– Pipeline Analytics 2023

$2,500.00$7,500.00

The 2023 Mellalta Meets report analyzes the HER2-Low Breast Cancer Therapies pipeline, highlighting the market opportunities and competitive landscape with over 30 companies developing pipeline drug profiles. The study marks a significant shift in breast cancer understanding, indicating over 50% of such cancers as HER2-low, thereby creating new prospects for therapeutic ADCs in treating HER2-low tumors. It also details the promising development pipeline involving a variety of ADCs and combination strategies to address this newly classified breast cancer subtype.

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Description

The HER2-Low Breast Cancer –Pipeline Analytics -2023 report published by Mellalta Meets covers the HER2-Low Breast Cancer Therapies market opportunity providing Key Competitive Analysis, 30+ Companies with Pipeline Drug Profiles, Clinical Trials, Other Developments (Collaboration Details, Funding, etc.), Licensing and Agreements, Business Agreement, Business Partner as well as Clinical Partner. Reports cover pipeline product analysis by stage of development, competitive landscape by phases, companies, therapy area and indication by phases. HER2-Low Metastatic Breast Cancer reports add value in terms of providing the description of clinical-stage products with respect to their clinical & regulatory timelines as well as in terms of providing the current market opportunity, drivers and challenges.

The introduction of HER2-low breast cancer represents a significant shift in the understanding and treatment of breast cancer. More than 50% of breast cancers are currently defined as “Human epidermal growth factor receptor 2 (HER2) low breast cancer (BC)”, with HER2 immunohistochemistry (IHC) scores of +1 or +2 with a negative fluorescence in situ hybridization (FISH) test. The changing treatment landscape has created new opportunities in the market for more companies to develop and commercialize the use of therapeutic ADCs in HER2-low tumors.

In this report, Mellalta Meets provides an in-depth analysis of the HER2-Low Breast Cancer Pipeline covering preclinical and clinical studies, details of partnerships and business deal values, targeted technologies and therapy areas, investments, and acquisition trends. Currently, there are more than 33+ candidates in the HER2-Low Breast Cancer Pipeline under evaluation in clinical and preclinical studies. The major key players operating in the market are Jiangsu HengRui Medicine, Duality Biologics, Yantai Rongchang Pharmaceutical, Gilead Sciences, AstraZeneca/Daiichi Sankyo and many more which have robust clinical pipeline of HER2-Low Breast Cancer candidates.

As per analysis, the development pipeline is full of different ADCs and combination approaches which can help in addressing this new subtype of Breast cancer.

Mellalta’s HER2-Low Breast Cancer Pipeline Report– Market Summary 

Report Attributes Details
Key Late Stage Market Players Jiangsu HengRui Medicine; Duality Biologics; Yantai Rongchang Pharmaceutical; Gilead Sciences; AstraZeneca/Daiichi Sankyo
Lead Assets Phase 3 (10+); Phase 2 (10+); Phase 1 (5+); Preclinical (3+); Discovery stages

Mellalta’s HER2-Low Breast Cancer Pipeline Report – Key Highlights

  • There are ~10 products in the Phase 3 stage of development, representing ~35% of the total share of the developing HER2-Low Breast Cancer Therapeutics landscape.
  • The pipeline of HER2-Low Breast Cancer therapies is dominated by the Phase III (10+) assets; Phase II (10+); Phase I (5+) and Preclinical (3+) and Discovery assets.
  • To be continued…

Report Coverage:

  • Indication Prioritization: HER2-Low Breast Cancer market potential based on Indications
  • Business Transactions & Strategies: Key collaborations and deal values
  • HER2-Low Breast Cancer Pipeline Development: Product Profiles, Clinical Trials & Results
  • HER2-Low Breast Cancer Acquisition Targets
  • HER2-Low Breast Cancer Competitive Intelligence
  • Recent and upcoming events

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Table of Contents

  • REPORT OVERVIEW
  • OVERVIEW
    • HER2-Low Breast Cancer – Overview
    • Diagnostic tools for HER2-Low Breast Cancer
    • AI-based HER2-low IHC scoring in breast cancer
    • Diagnostic tools for HER2-Low Breast Cancer detection: Limitations
    • Current Challenges with HER2-Low Breast Cancer
  • HER2-LOW BREAST CANCER PIPELINE ANALYSIS
    • Overview
    • Assets by Indication/Phase
    • Pipeline Products by Stage of Development
    • HER2-Low Breast Cancer Competitive Landscape
    • Pipeline Products by Company and Phases
    • HER2-Low Breast Cancer Clinical & Regulatory Timelines
  • HER2-LOW BREAST CANCER ACQUISITIONS, LICENSING AND COLLABORATION DEALS
    • HER2-Low Breast Cancer Acquisitions, Licensing and Deal values
    • HER2-Low Breast Cancer Acquisitions, Licensing by Transaction type and total amount size by Phases
    • Promising Technologies Under development
  • HER2-Low Breast Cancer PIPELINE LANDSCAPE
    • Profile at Glance
    • Late-Stage Assets Comparisons At–a–glance
    • HER2-Low Breast Cancer Pipeline Drug Profiles
    • Phase III
      • Duality Biologics: DB-1303
        • Product Profile & Description
        • Collaborations
        • Other Developments
        • Clinical Trials
      • Jiangsu HengRui Medicine: Trastuzumab rezetecan
        • Product Profile & Description
        • Collaborations
        • Other Developments
        • Clinical Trials
      • RemeGen/Seagen: Disitamab vedotin
        • Product Profile & Description
        • Collaborations
        • Other Developments
        • Clinical Trials
      • Others…
    • Phase II
      • Miracogen: MRG002
        • Product Profile & Description
        • Collaborations
        • Other Developments
        • Clinical Trials
      • Merus: MCLA-128
        • Product Profile & Description
        • Collaborations
        • Other Developments
        • Clinical Trials
      • Others…
    • Phase I
      • Sichuan Baili Pharmaceutical/SystImmune: BL-M07D1
      • Product Profile & Description
      • Collaborations
      • Other Developments
      • Clinical Trials
    • HighField Biopharmaceuticals Corporation: HF158K1
      • Product Profile & Description
      • Collaborations
      • Other Developments
      • Clinical Trials
    • Others…
  • HER2-LOW BREAST CANCER MARKET OVERVIEW
  • Current Market Scenario
    • Market Potential of HER2-Low Breast Cancer Market
    • Market Potential of HER2-Low Breast Cancer Market Barriers & Challenges
  • HER2-LOW BREAST CANCER FUTURE PROSPECTS
  • SWOT ANALYSIS
  • APPENDIX